Rotterdam, Netherlands
Scientific programme
Saturday 22 June
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12:00-19:30 |
Registration |
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14:00-17:00 |
Training course: Bone – Bedside to Bench and Back |
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14:00-14:30 |
What does a basic bone scientist need to know about clinical bone disease in children? |
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Nick Bishop (Sheffield, UK) |
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14:30-15:00 |
What does a clinical bone scientist need to know about basic bone biology? |
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Harald Jüppner (Boston, USA) |
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15:00-17:00 |
Approaches to: Includes case discussions |
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15:00-16:00 |
Hypogonadal bone diseases |
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Convenor: Coen Netelenbos (Amsterdam, Netherlands) |
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Speakers: |
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Wolfgang Högler (Birmingham, UK) |
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Annemieke Boot (Groningen, Netherlands) |
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16:00-17:00 |
Phosphate metabolism and bone diseases |
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Convenor: Craig B Langman (Chicago, USA) |
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Speakers: |
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Rachel Gafni (Bethesda, USA) |
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Farzana Perwad (San Francisco, USA) |
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17:00-17:15 |
Break |
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17:15-17:30 |
Welcome |
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17:30-18:00 |
Keynote Lecture |
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The past, the present and the future of pediatric bone research |
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Francis Glorieux (Montreal, Canada) |
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18:00-19:00 |
Welcome Reception |
Sunday 23 June
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08:30-10:30 |
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The Fracturing Child: Epidemiology |
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08:30-09:00 |
IS1 |
Bone mass and other determinants of fractures in children and adolescents |
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Emma Clark (Bristol, UK) |
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09:00-09:30 |
IS2 |
Epigenetic influences on childhood fractures |
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Kassim Javaid (Oxford, UK) |
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09:30-10:00 |
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Oral Communications: Epidemiology |
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09:30 |
OC1 |
The Amalgamated Paediatric Bone Density Study (The ALPHABET Study) - The collation and generation of UK based reference data for paediatric bone densitometry |
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09:40 |
OC2 |
Fracture patterns and bone mass in South African adolescent-mother pairs: The Birth to Twenty Cohort |
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09:50 |
OC3 |
Pediatric differences in Bone Mineral Density according to ethnic background in children: the Generation R Study |
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10:00 |
OC4 |
Maternal antenatal 25(OH)-vitamin D status is associated with offspring muscle strength at 4 years of age |
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10:10 |
OC5 |
Novel musculoskeletal phenotypes during childhood for epidemiological studies |
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10:20 |
OC6 |
Role of bone-associated loci identified in GWAS meta-analyses in the context of longitudinal pediatric BMD in European Americans |
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10:30 |
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Charles Slemenda Award |
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10:35-11:00 |
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Coffee |
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11:00-13:00 |
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The Fracturing Child: Biology |
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11:00-11:30 |
IS3 |
Bone structure and fractures |
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Salman Kirmani (Rochester, USA) |
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11:30-12:00 |
IS4 |
The biology of bone revealed through bone biopsy |
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Katherine Wesseling-Perry (Los Angeles, USA) |
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12:00-13:00 |
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Oral Communications: Biology |
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12:00 |
OC7 |
The PPP6R3/LRP5 locus influences lean mass in children of different ethnic background and highlights pleiotropic effects and muscle-bone interactions |
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12:10 |
OC8 |
Generation of the first mouse model of Autosomal Dominant Type II Osteopetrosis (ADO2) harbouring the pG213R-clc7 mutation |
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12:20 |
OC9 |
EPO signaling and hematopoietic expansion as causes of osteoporosis in a thalassemia mouse model |
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12:30 |
OC10 |
Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone |
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12:40 |
OC11 |
Connectivity Map-based discovery of novel compounds that induce osteoblast differentiation |
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12:50 |
OC12 |
Improvement of collagen synthesis in fibroblasts of Brtl model for Osteogenesis Imperfecta following lentiviral-shRNA-mediated down-expression of mutant Col1a1 allele |
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13:00-13:30 13:30-14:30 |
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Lunch Posters (odd numbers presented) |
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14:30-15:45 |
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Oral Posters |
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14:30 |
OP1 |
Skeletal effects of Hypothyroidism are mediated by Thyroid Hormone Receptor α |
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14:35 |
OP2 |
High FSH serum levels may support the altered bone remodeling in Turner Syndrome patients |
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14:40 |
OP3 |
Calcimimetics as adjunct therapy in XLH: 18 months experience |
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14:45 |
OP4 |
A new start-codon in IFITM5 causes Osteogenesis Imperfecta Type V |
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14:50 |
OP5 |
Abstract withdrawn |
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14:55 |
OP6 |
Children with nephrotic syndrome have increased tibial bone area but similar volumetric bone mineral density to healthy controls |
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15:00 |
OP7 |
Bone Mineralization Density Distribution, bone formation rate and bone turnover markers in a cohort of children with CKD before and after growth hormone treatment |
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15:05 |
OP8 |
Quantitative measurement of abnormal bone quality and strength with bone micro-architecture and rod-plate configuration in osteopenic adolescent idiopathic scoliosis (AIS) |
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15:10 |
OP9 |
Anticalciuric effect of recombinant PTH in patients with activating mutations of the calcium-sensing receptor causing autosomal dominant hypocalcaemia-hypercalciuria (ADHH) |
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15:15 |
OP10 |
Metacarpal width, length, medullary diameter and cortical thickness in Hypophosphatemic Rickets |
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15:20 |
OP11 |
Artistic gymnasts display micro-architectural advantages over trampolining and tumbling gymnasts: A high resolution peripheral quantitative computed tomography study |
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15:25 |
OP12 |
The bone/vessels interplay in teenagers with chronic kidney disease |
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15:30 |
OP13 |
Long-term effects of bisphosphonate therapy in children with osteogenesis imperfecta |
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15:35 |
OP14 |
Inflammation and glucocorticoid therapy impair skeletal modeling during growth following Crohn Disease diagnosis |
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15:40 |
OP15 |
Dissecting the role of osteoblast derived nitric oxide in bone remodeling |
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15:45-16:15 |
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Coffee |
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16:15-17:45 |
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Rare diseases |
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16:15-16:45 |
IS5 |
Acrodysostosis |
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Agnes Linglart (Paris, France) |
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16:45-17:15 |
IS6 |
Gaucher |
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Maja Di Rocco (Genoa, Italy) |
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17:15-17:45 |
IS7 |
Osteogenesis Imperfecta |
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Gerard Pals (Amsterdam, Netherlands) |
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17:45-18:00 |
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Break |
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18:00-20:00 |
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Dinner Symposium: |
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Welcome/Introduction/Case Introduction |
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New insights on vitamin D metabolism: the role of 24-hydroxylase |
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Hormone independent hypercalcemia: Jansen’s |
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Hypophosphatasia: the Impact of alkaline phosphatase deficiency |
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Case Discussion: pathogenesis and differential diagnosis |
Monday 24 June
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08:30-10:30 |
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The Fracturing Child: Diagnostics |
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08:30-09:00 |
IS8 |
Non-invasive assessment of bone structure and strength using QCT and MRI |
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Mary Leonard (Philadelphia, USA) |
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09:00-09:30 |
IS9 |
DXA and Vertebral Fracture Assessment |
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Judith Adams (Manchester, UK) |
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09:30-10:30 |
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Oral Communications: Diagnostics |
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09:30 |
OC13 |
Level of calcium intake modifies the correlation between parathyroid hormone and 25-hydroxyvitamin D: A proposal of adequate 25-hydroxyvitamin D levels in children |
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09:40 |
OC14 |
What DXA measurement sites are best for bone health assessment in children? Effect of inter-machine differences on bone outcomes from the Bone Mineral Density in Childhood Study (BMDCS) |
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09:50 |
OC15 |
Bone Health Index: Swiss children have less in the bank than a generation ago |
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10:00 |
OC16 |
Longitudinal analysis of volumetric density, size and strength towards the end of skeletal maturation in Gambian males habituated to low calcium intake |
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10:10 |
OC17 |
Determinants of bone mineral density in long-term adult survivors of childhood cancer |
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10:20 |
OC18 |
Trabecular bone score (TBS) applied to normal children's lumbar spine DXA scans |
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10:30-11:00 |
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Coffee |
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11:00-13:00 |
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The Fracturing Child: Therapeutics |
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11:00-11:30 |
IS10 |
Medical therapies: present and future |
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Craig Munns (Sydney, Australia) |
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11:30-12:00 |
IS11 |
Other therapeutic options: nutrition, vitamin D, physical activity |
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Catherine Gordon (Boston, USA) |
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12:00-13:00 |
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Oral Communications: Miscellaneous |
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12:00 |
OC19 |
New therapeutic approach in OI VI - suppression of bone resorption using the RANKL antibody denosumab |
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12:10 |
OC20 |
Exercise completed when young provides lifelong benefit to cortical bone structure and estimated strength |
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12:20 |
OC21 |
A randomized, double-blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone |
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12:30 |
OC22 |
Prolidase deficient mice are osteoporotic in early life |
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12:40 |
OC23 |
Switching from alendronate to RANKL blockade alters bone properties after 14 weeks of therapy in the oim/oim mouse |
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12:50 |
OC24 |
Fibroblast growth factor 23 (FGF23) plasma levels are elevated with early chronic kidney disease (CKD) and positively associated with steroid based (SB) versus steroid free (SF) immunosuppression in pediatric (ped) renal transplant (Tx) patients (pts) |
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13:00-13:30 13:30-14:30 |
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Lunch Posters (even numbers presented) |
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14:30-15:30 |
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Chronic diseases 1 |
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14:30-15:00 |
IS12 |
IBD, bone, fractures and inflammation |
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Susanne Schmidt (Gothenburg, Sweden) |
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15:00-15:30 |
IS13 |
Muscle-bone interaction in pediatric bone diseases |
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Frank Rauch (Montreal, Canada) |
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15:30-16:00 |
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Coffee |
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16:00-17:30 |
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Chronic diseases 2 |
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16:00-17:00 |
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Oral Communications: Chronic diseases |
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16:00 |
OC25 |
Wnt/ ß-catenin: A candidate pathway for bone repair in Neurofibromatosis Type-1 |
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16:10 |
OC26 |
Vertebral fractures in the 3 year period following steroid initiation among children with chronic illnesses |
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16:20 |
OC27 |
Serum vitamin D level can affect the treatment outcome of whole-body vibration (WBV) for low bone mass in girls with Adolescent Idiopathic Scoliosis (AIS) |
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16:30 |
OC28 |
Bone mineral density at diagnosis determines fracture rate in children treated according to the DCOG-ALL9 protocol. |
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16:40 |
OC29 |
Mineral metabolism, cortical volumetric bone mineral density and fracture risk in childhood chronic kidney disease |
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16:50 |
OC30 |
Alteration of Wnt/Beta-Catenin signaling in HIV-infected youths: A mechanism leading to impaired bone health? |
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17:00-17:30 |
IS14 |
Type I Diabetes |
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Susanne Bechtold (Munich, Germany) |
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17:30-19:00 |
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Satellite Symposium |
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Global burden of vitamin D deficiency |
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Food based strategies for increasing vitamin D status in young children |
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Vitamin D deficiency in adolescence |
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Buses depart for Conference Party immediately following Satellite Symposium |
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19:30-23:00 |
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Conference Party |
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Tuesday 25 June
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08:30-08:40 |
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Awards |
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| 08:40-09:00 | Late Breaking Abstracts | ||
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08:40 |
LB1 |
Influence of age and gender on spine bone density and TBS microarchitectural texture parameters in infants |
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08:50 |
LB2 |
WNT1mutations in early-onset osteoporosis and osteogenesis imperfecta identify a key WNT ligand regulating bone mass Outi Mäkitie (Helsinki, Finland) |
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09:00-10:20 |
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Paediatric cancer and bone: Round Table |
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09:00-09:30 |
IS15 |
Bone and endocrine side-effects in childhood Hodgkins lymphoma and acute lymphoblastic leukemia |
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Marry van den Heuvel-Eibrink (Rotterdam, Netherlands) |
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09:30-10:00 |
IS16 |
Childhood cancer and fractures |
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Carmen Wilson (Memphis, USA) |
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10:00-10:20 |
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Round Table discussion |
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10:20-10:45 |
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Coffee |
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10:45-12:05 |
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Obesity as a bone disease: Round Table |
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10:45-11:15 |
IS17 |
Bone as an endocrine organ |
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Paul Baldock (Sydney, Australia) |
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11:15-11:45 |
IS18 |
Obesity and skeletal health |
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Paul Dimitri (Sheffield, UK) |
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11:45-12:05 |
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Round Table discussion |
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12:05 |
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Close |
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Posters
OP1-OP15
As listed on the Programme, Sunday 14:30-15:45
P1
Abstract withdrawn
P2
Abstract withdrawn
P3
Abstract withdrawn
P4
Abstract withdrawn
P5
Camptodactyly-arthropathy-coxa vara-pericarditis syndrome: Clinical and molecular genetic findings
Sulaiman Al-Mayouf (Riyadh, Saudi Arabia)
P6
The relationship between bone health and body composition profile in patients with galactose metabolic disorders: implications for practice
Artemis Doulgeraki (Athens, Greece)
P7
Osteometric parameters of mature rats mandible molars when implanted in the tibia biogenic hydroxyapatite, saturated with iron
Morozov Vitaly (Luhansk, Ukraine)
P8
Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia
Christine Hofmann (Würzburg, Germany)
P9
A 6-month intervention study with vibration therapy in severely disabled children: effects on bone, biochemical markers and acceptance
Diana Swolin-Eide (Gothenburg, Sweden)
P10
Osteoorosis in young patients with neurological impairments
Yasser Yaghi (Saida, Lebanon)
P11
Abstract withdrawn
P12
DXL measurements in children 2 - 10 years
Ann-Charlott Söderpalm (Göthenburg, Sweden)
P13
Bone turnover compensates for the delayed growth in small for gestational age neonates
Roxane Tenta (Athens, Greece)
P14
Bone status and body composition analysis in young patients with phenylketonuria and hyperphenylalaninemia
Artemis Doulgeraki (Athens, Greece)
P15
Osteogenesis Imperfecta-bone mass acquisition under bisphosphonates treatment and additional gain in BMD in time of rhGH treatment for growth delay
Corina Galesanu (IASI, Romania)
P16
Bone size and bone mineral content in adolescents and young adults with eating disorders
Sheila Shepherd (Glasgow, UK)
P17
The optimal dose of vitamin D in growing girls during academic years: a randomized trial
Samane Tefagh (Yazd, Iran)
P18
Influence of anthropometric parameters on assessment of paediatric bone mineral density and bone mineral content
Thomas Hangartner (Dayton, USA)
P19
Positive correlation of serum vitamin D status with bone density and bone quality among adolescent girls in Hong Kong
Tsz Fung Cheung (Hong Kong, Hong Kong)
P20
Assessment of Vitamin D nutrition status & dietary calcium intake in children 2-5 years of age
Priyanka Kureel (New Delhi, India)
P21
Bone disease in Children with Geroderma Osteodysplasticum (GO) – A 25 year experience from a single tertiary centre
Jaya Sujatha Gopal-Kothandapani (Manchester, UK)
P22
Association of volumetric bone mineral density, bone morphometry and trabecular bone micro-architecture with leptin and soluble leptin receptor in adolescent idiopathic scoliosis
Elisa MS Tam (Hong Kong, Hong Kong)
P23
Abstract withdrawn
P24
Effects of endurance training on somatic growth in a rat model of chronic kidney disease (CKD) related growth retardation
Daniel Landau (Beer Sheva, Israel)
P25
Maternal bone density and rickets in Nigerian children
Jennifer Hsu (Rochester, USA)
P26
Improvement in valgus deformity in hypophosphatemic rickets due to primary de Toni-Debré-Fanconi syndrome treated with phosphate, calcitriol and alkali therapy
Sasigarn Bowden (Columbus, USA)
P27
Randomized-controlled study in kidney transplanted children: early withdrawal of corticoids: effect on bone health recovery
Maria Loreto Reyes (Santiago, Chile)
P28
Vitamin D insufficiency and its correlation with low bone mass in Adolescent Idiopathic Scoliosis (AIS)
Tsz Ping Lam (Hong Kong SAR, China)
P29
Coping with Osteogenesis Imperfecta; What kind of difficulties are families living with?
Leyla Baysan Arabacı (İzmir, Turkey)
P30
The effect of psychoeducation in families with Osteogenezis Imperfecta
Sati Bozkurt (İzmir, Turkey)
P31
Craniofacial consequences of high dose zoledronic acid injections in onco-pediatric patients
Frederic Lezot (Nantes, France)
P32
The effect of vitamin D supplementation on calcium excretion in Thalassemia
Maria Vogiatzi (New York, USA)
P33
Patients with mutations in PHEX or FGF23 share FGF23 excess but present distinct bone and mineral metabolism features
Agnès Linglart (Le Kremlin Bicêtre, France)
P34
Reliability of pQCT scan protocol of second metatarsal for children with Juvenile Idiopathic Arthritis
David Greene (Strathfield, Australia)
P35
Six monthly intravenous zoledronic acid in childhood osteoporosis
Andrew Biggin (Westmead, Australia)
P36
Vitamin D deficiency and its relationship to parathyroid hormone in morbidly obese adolescents prior to bariatric surgery
Marisa Censani (New York, USA)
P37
Reduction in bisphosphonate side effect profile using short term steroid cover
Andrew Biggin (Westmead, Australia)
P38
Abnormal bone quality in both cortical and trabecular compartments in Adolescent Idiopathic Scoliosis (AIS)
Wing Sze Yu (Hong Kong, Hong Kong)
P39
Prevalence of vitamin D deficiency in adolescent Muslim girls attending a school in the UK which adheres to a conservative dress code
M Zulf Mughal (Manchester, UK)
P40
Altered bone metabolism in obese children: the pathogenic role of adipocytokines and inflammation
Pawel Abramowicz (Bialystok, Poland)
P41
Management of a new case of neonatal hypocalciuric hypercalcemia related to mutation of the calcium-sensing receptor gene with bone abnormalities
Thomas Edouard (Toulouse, France)
P42
The effect of glucocorticoids on bone indices in children with rheumatic and oncological medical conditions
Jennifer Harrington (Toronto, Canada)
P43
Bone quality in young thalassaemic patients
Alberto Argentiero (Mesagne, Italy)
P44
A homozygous mutation in the DNA binding domain of human vitamin D receptor causes vitamin D resistant rickets
Bram van der Eerden (Rotterdam, Netherlands)
P45
Bone mineral density impairment in Marfan syndrome: a hidden and neglected issue
Giuliana Trifiro (Milan, Italy)
P46
Interactions of adipokines and bone metabolism in patients with severe juvenile idiopathic arthritis
Kati Markula-Patjas (Tampere, Finland)
P47
Vitamin D deficiency and structural and functional state of bone tissue in schoolchildren of Ukraine
Vladyslav Povoroznyuk (Kyiv, Ukraine)
P48
Pubertal induction with testosterone of a boy with bilateral anorchia guided by the development of his monozygotic twin brother
Eva Van Caenegem (Ghent, Belgium)
P49
Some features of regulation of the bone tissue metabolisms at the newborns who have transferred infectious influence during intrauterine development
Gulsym Manasova (Kyiv, Ukraine)
P50
Bioelectrical impedence as a screening tool for low bone mass in Indian children and adolescents
Veena Ekbote (Pune, India)
P51
Mild visual impairment in a 13 year old child with Osteoporosis-Pseudoglioma Syndrome
Moira Cheung (London, UK)
P52
Incidence of fractures in 2 to 18 year old affluent Indian children: a multicentre study
Veena Ekbote (Pune, India)
P53
The Influence of anthropometry and body composition on children’s bone health: The Childhood Health, Activity and Motor Performance School (The CHAMPS) study, Denmark
Malene Heidemann (Odense C, Denmark)
P54
Association of calcium and dairy intake with growth in Indian children and adolescents
Veena Ekbote (Pune, India)
P55
Body composition, anthropometric parameters and bone densitometry in young Ukrainian male
V Luzin (Luhansk, Ukraine)
P56
Effect of puberty on the muscle-bone relationship in Indian children and adolescents
Anuradha Khadilkar (Pune, India)
P57
Heterozygous mutation in GALNT3 in a case of Hyperphosphataemic Familial Tumoral Calcinosis
Katie Knight (London, UK)
P58
Puberty is critical for the development of bone mineral density impairment in patients with congenital adrenal hyperplasia
Stefano Mora (Milan, Italy)
P59
The rapid effect of vibration on bone formation and resorption in the growing skeleton
Nick Bishop (Sheffield, UK)
P60
Failure of free, public vitamin D supplementation program for Quebec infants - temporal trends and significant predictors
Celia Rodd (Montreal, Canada)
P61
Elevated FGF23 levels In premature infants without excessive phosphaturia
Celia Rodd (Montreal, Canada)
P62
The effect of the ketogenic diet on the developing skeleton
Peter Simm (Parkville, Australia)
P63
Bone status of Indian children and adolescents with Type 1 Diabetes Mellitus
Lavanya Parthasarathy (Pune, India)
P64
The level of vitamin D and calcium in urban pregnant women in Russian Federation
Olga Ershova (Yaroslavl, Russia)
P65
Improvement in morphological properties of trabecular bones and longitudinal growth in tibia for growing rats through an impact stimulation
Sinae Eom (Seoul, Republic of Korea)
P66
Effect of resistance training on peripheral bone mineral density and muscle strength in adolescents with motor difficulties
Beth Hands (Fremantle, Australia)
P67
Dual Energy X-Ray Absorptiometry in predicting clinical bone disease in adults with childhood onset end-stage renal disease
Maike van Huis (Amsterdam, Netherlands)
P68
Engineered tridimensional hydroxyapatite scaffold to support bone resorption
Alfredo Cappariello (Rome, Italy)
P69
sRANKL/OPG in children with Idiopathic Hypercalciuria
Anna Challa (Ioannina, Greece)
P70
Isolated bilateral zeugo-autopodal segments agenesis of the lower limb: Unusual malformation case report
Antoine Christiaens (Brussels, Belgium)
P71
The microarchitecture of bone in osteochondromas
Heleen Staal (Maastricht, Netherlands)
P72
Abstract withdrawn
P73
Histomorphometric parameters of the alveolar ridges of the mandible in immature rats after thymectomy
V Luzin (Luhansk, Ukraine)
P74
Assessment of bone mass and bone metabolism in children with chronic inflammatory bowel diseases
Vesna Kusec (Zagreb, Croatia)
P75
Vitamin D Receptor Gene Fok1 Polymorphism and bone mass accrual in Indian girls
Anuradha Khadilkar (Pune, India)
P76
Final height and bone health in young adults, transplanted in childhood
Maria Van Dyck (Leuven, Belgium)
P77
A novel mutation in CRTAP gene in a patient with severe Ostegenesis imperfecta type VII
Ilkka Vuorimies (Helsinki, Finland)
P78
Variable relationship of fat mass and bone with pubertal staging in obese and normal weight Indian children and adolescents
Anuradha Khadilkar (Pune, India)
P79
High sedentary lifestyle practices has adverse influence on musculoskeletal health in adolescent boys and girls - findings from a population-based study in Malaysia
Pey Sze Teo (Kubang Kerian, Malaysia)
P80
Osteogenesis imperfecta and short stature: effect of sclerostin antibody treatment in oim/oim mice
Mickaël Cardinal (Brussels, Belgium)
P81
Reference point indentation testing detects age-related changes in tissue mechanical properties in mice
Peter Grabowski (Sheffield, UK)
P82
The influence of sclerostin serum levels on bone mineral density and body composition in patients with Rett syndrome and healthy adolescent girls
Carla Caffarelli (Siena, Italy)
P83
Anti-RANKL Nanobody® ALX-0141 shows sustained biomarker inhibition in a Phase I study in healthy postmenopausal women
Pieter Schoen (Zwijnaarde, Belgium)
P84
Comparison of socioeconomic status on bone mass assessed by Quantitative ultrasound of hand phalanges of boys from 7 to 15 years old
Luiz Carlos de Barros Ramalho (Campinas, São Paulo, Brazil)
P85
Comparison of socioeconomic status on bone mass assessed by quantitative ultrasound of the phalanges in girls from 7 to 15 years old
Juan Eduardo Samur-San-Martin (Campinas, Brazil)
P86
Assessing bone quality and fracture resistance in children using microindentation
Peter Grabowski (Sheffield, UK)
P87
Serum homocysteine levels in children and adolescents with impaired bone health
Stepan Kutilek (Pardubice, Czech Republic)
P88
Children and adolescents with cystic fibrosis have normal volumetric BMD and geometry at the radius, but low muscle area at the forearm
Ondrej Soucek (Prague, Czech Republic)
P89
Painful vertebral fractures during pregnancy: be aware of a potentially underlying genetic cause
Carola Zillikens (Rotterdam, Netherlands)
P90
Intravenous pamidronate in the treatment of severe idiopathic infantile hypercalcemia
Sylva Skalova (Pardubice, Czech Republic)
P91
Hypovitaminosis D in chronically ill children in Greece and its management
Damiani Tsiamasfirou (Athens, Greece)
P92
Bone mineralization in children with chronic gastroduodenitis
Larisa Scheplyagina (Saint-Petersburg, Russia)
P93
Long term efficacy of low dose pamidronate treatment in Osteogenesis Imperfecta and its effects on growth
Damla Goksen (İzmir, Turkey)
P94
Bone anomalies in Noonan syndrome
Ioana Bodescu (Ioana, Romania)
P95
Abstract withdrawn
P96
Cross-sectional associations of sex steroids with bone maturation, bone mineral density and bone geometry in boys
Sara Vandewalle (Ghent, Belgium)
P97
Vitamin D status and bone health in survivors of childhood lymphoblastic leukemia
Michael M Schündeln (Essen, Germany)
P98
Effects of Denosumab on bone biochemistry and calcium metabolism in a girl with juvenile Paget’s Disease
Corinna Grasemann (Essen, Germany)
P99
Potential association between vitamin D deficiency and hypertension in adolescents: a pilot study
Jerzy Konstantynowicz (Bialystok, Poland)
P100
Preliminary evidence of reduced Volumetric Trabecular Bone Mineral Density in children with Idiopathic Hypercalciuria. A Peripheral Quantitative Computed Tomography (pQCT) study
Erato Atsali (Athens, Greece)
P101
Rapid bone mass recovery after parathyroidectomy for primary hyperparathyroidism in a 15-year-old boy
Cristina Tau (Buenos Aires, Argentina)
P102
Influence of nutritional status in the bone mass assessed by Quantitative Ultrasonography (QUS) of boys
Vinícius Justino de Oliveira Barbeta (Campinas, Brazil)
P103
Celiac disease and bone disorders: diagnosis age influence
Oscar Brunetto (Buenos Aires, Argentina)
P104
Immunohistochemical localization of bone morphogenetic proteins and their receptors in human osteochondromas
Araceli Cuellar (Sacramento, USA)
P105
Bisphosphonate treatment in non-ambulatory patients with spastic quadriplegic cerebral palsy and other neuromuscular disorders: effectiveness of pamidronate vs zoledronic acid
Sasigarn Bowden (Columbus, USA)
P106
Acquired hypophosphatemic rickets in a 13 year-old boy presenting with knee pain and valgus deformity
Sasigarn Bowden (Columbus, USA)
P107
Bone cross-sectional geometry and volumetric density at the distal radius in female adolescents with anorexia nervosa
Inge Roggen (Jette, Belgium)
P108
Antenatal glucocorticoid injections do not aggravate stress-induced bone loss in young adult mice
Holger Henneicke (Concord, Australia)
P109
Vertebral morphology assessment in children: can a modified algorithm-based qualitative technique be used reliably?
Ese Adiotomre (Leeds, UK)
P110
Replacing conventional spine radiographs with dual energy x-ray absorptiometry (DXA) in children with suspected reduction in bone density
Ese Adiotomre (Leeds, UK)
P111
Vitamin D status and Association to bone health in 781 healthy 8-11 year old Danish school children - preliminary results from the OPUS School Meal Study
Rikke Petersen (Frederiksberg C, Denmark)
P112
Abstract withdrawn
P113
Everyday chemicals modulate bone properties during development
Maria Herlin (Stockholm, Sweden)
P114
Association between parameters of bone mass measured by dual energy X-ray absorptiometry and quantitative ultrasound of proximal phalanges in children and adolescents with congenital adrenal hyperplasia
Ezequiel M Gonçalves (Campinas, Brazil)
P115
Bone mineral density in late adolescence of transsexuals treated with GnRH-analogues in their teens
Martine Caris (Amsterdam, Netherlands)
P116
Vitamin D dependent rickets type 1 (VDDR-1): two years after discontinuation of treatment
Victoria Kougia (Thessaloniki, Greece)
P117
Impact of age and pubertal development on bone mass assessed by quantitative ultrasound of the proximal phalanges in boys and girls aged 10 to 14 years
Tathyane Krahenbuhl (Campinas, Brazil)
P118
Variation in response to vitamin D therapy in a series of consecutive children referred to a paediatric bone disease service
Fawaz Arshad (Sheffield, UK)
P119
Depressive symptoms and bone mineral density in a cohort of Portuguese adolescents: no association
Teresa Monjardino (Porto, Portugal)
P120
Osteoblasts communicate with their neighbouring cells via extracellular vesicles
Jess Morhayim (Rotterdam, Netherlands)
P121
Tibial metaphyseal shape varies between children according to history of fracture
Paul Arundel (Sheffield, UK)
P122
Fasting total Ghrelin levels are increased in patients with adolescent idiopathic scoliosis (AIS)
Isabelle Gennero (Toulouse, France)
P123
Inadequately treated hypophosphataemic rickets (HR) in 14-year-old boy: a case report
Athanasios Athanasakos (Athens, Greece)
P124
Adipokines and bone turnover throughout adolescence: an exploratory approach in a cohort of girls
Teresa Monjardino (Porto, Portugal)
P125
Growth plate modifications in lysophosphatidic acid (LPA) LPA1 receptor-invalidated mice
Jean-Pierre Salles (Toulouse, France)
P126
The role of severity of growth hormone deficiency on clinical and instrumental features and response to treatment in children
Anzhalika Solntsava (Minsk, Belarus)
P127
Mechanosensitive TRP channels are essential for Ca2+ signaling in osteoclastogenesis
Yu-Mi Yang (Seoul, Republic of Korea)
P128
Bone mineral density in survivors of childhood lymphoma
Eryk Latoch (Bialystok, Poland)
P129
Radiographic evidence of rapid healing of vitamin D deficient rickets after 2 weeks of therapy
Kathryn Stephens (Columbus, USA)
P130
"Bone in bone" sign in Juvenile Osteoporosis (IJO) in a 13-year-old girl
Athanasios Athanasakos (Athens, Greece)
P131
Ghrelin differentiates human osteoblasts via GHS-R1a receptor
Isabelle Gennero (Toulouse, France)
P132
Studies on bone and osteoclasts in patients with Shwachman Diamond Syndrome
Miep Helfrich (Aberdeen, UK)
P133
Linear growth over 2 years of velaglucerase alfa therapy in children with type 1 Gaucher disease previously treated with imiglucerase
Ari Zimran (Jerusalem, Israel)
P134
Cessation of ambulation results in a dramatic loss of trabecular bone density in boys with Duchenne Muscular Dystrophy (DMD)
Nicola Crabtree (Birmingham, UK)
P135
Is Vertebral Fracture Assessment by DXA more useful in a high fracture risk paediatric population than in a low risk screening population?
Nicola Crabtree (Birmingham, UK)
P136
Time to low bone mass occurrence in children diagnosed with acute lymphoblastic leukemia
Katarzyna Muszynska-Roslan (Bialystok, Poland)
P137
Influence of nutritional status in the bone mass assessed by Phalangeal Quantitative Ultrasound of girls aged 7 to 10 years old
Fabio Bertapelli (Campinas, Brazil)
P138
Rare mutations associated with osteoclast-poor osteopetrosis provide molecular insights into receptor activator of NFκβ signalling
Julie Crockett (Aberdeen, UK)
P139
How to cope with a case of heterotopic ossifications
Grazia Morandi (Cesole di Marcaria, Italy)
P140
Defects of SERPINF1 cause progressively deforming recessive Osteogenesis Imperfecta with normal collagen I
Giacomo Venturi (Verona, Italy)
P141
Novel splicing mutation in FKBP10 gene in a patient with moderate/severe form of osteogenesis imperfecta
Giacomo Venturi (Verona, Italy)
P142
A case of geleophysic dysplasia
Claudia Piona (Verona, Italy)
P143
Fractures in juvenile idiopathic arthritis children: role of disease activity and genetic factors
Mikhail Kostik (Saint-Petersburg, Russia)
P144
Long rerm bone sequelae following severe meningococcal septicaemia
Shaila Sukthankar (Manchester, UK)
P145
The recurrent IFITM5 c.-14C>T transition which causes osteogenesis imperfecta type V occurs at a highly methylated CPG dinucleotide: a novel mutational hot-spot?
Elena Monti (Verona, Italy)
P146
A case of familial cherubism
Evelina Maines (Verona, Italy)
P147
A case of gorham-stout syndrome with Chylothorax
Claudia Piona (Verona, Italy)
P148
Low bone mineral density in a group of girls with Rett syndrome
Steven Bachrach (Wilmington, USA)
P149
Bone mineral content in healthy Danish children assessed by DXA-scanning and by computerised determination from hand radiographs
Anders Schou (Fredericia, Denmark)
P150
Markers of bone turnover in obese children - relationship to the nutritional status and oxidative stress level
Pawel Matusik (Katowice, Poland)
P151
Severity of spine deformity in children and adolescents with idiopathic scoliosis (IS) is associated with nutritional status and body composition
Pawel Matusik (Katowice, Poland)
P152
Zinc supplementation improves bone density in young adults with thalassemia
Ellen B Fung (Oakland, USA)
P153
Low urinary citrate: a risk factor for fragility fractures in children and adolescents
Jarzy Konstantynowicz (Bialystok, Poland)
P154
Smad4 regulates growth plate chondrocyte proliferation, columnar organization and proteoglycan synthesis
Amanda Whitaker (San Francisco, USA)
P155
Assessment of bone density in MPS IV (Morquio Disease)
Heidi Kecskemethy (Wilmington, USA)
P156
Reflection analysis of infant scans results may improve infant DXA bone density and body composition result that contain motion
John Shepherd (Fairfax, USA)
P157
Growth and bone health after hematopoietic stem cell transplantation or tyrosine kinase inhibitors in children with chronic myeloid leukemia: a single institution experience
Kimberley Dilley (Chicago, USA)
P158
Exploring vertebral abnormalities in patients with thalassemia and sickle cell disease
Ellen Fung (Oakland, USA)
P159
Novel SLC34A3 mutation causing mild Hypophosphataemia, Hypercalciuria & Nephrolithiasis but no clinical or radiological evidence of Rickets
Caroline Steele (Manchester, UK)
P160
A familial case of Osteogenesis Imperfecta: study of genotype-phenotype correlation.
Maria Luisa Bianchi (Milan, Italy)
P161
Autoimmune hepatitis and bone density in children
Silvia Vai (Milan, Italy)
P162
Low bone mass and fractures in young patients with chronic diseases
Maria Luisa Bianchi (Milan, Italy)
P163
Phenotype-genotype correlation and role of ancillary investigations in atypical and rare forms of Osteogenesis Imperfecta
Meena Balasubramanian (Sheffield, UK)
P164
Vitamin D deficiency in Moscow children and adolescents
Dmitry Shilin (Moscow, Russia)
P165
Morquio disease in two sisters: Clinical case
Liliana Mejia de Beldjenna (Cali, Colombia)
P166
Severe metabolic bone disease of prematurity following a brief period of continuous veno-veno haemofiltration (CVVH)
Nick Bishop (Sheffield, UK)
P167
Recurrent fractures and low bone mass in a patient with new mutation of LRP5 gene
Agnieszka Rusinska (Lodz, Poland)
P168
Osteogenesis imperfecta - diagnostic difficulties due to clinical symptoms diversity – the results of own studies
Agnieszka Rusinska (Lodz, Poland)
P169
Milk, childhood and postmenopausal osteoporosis
Antonio Bazarrra-Fernandez (La Coruña, Spain)
P170
Achondroplasia: medical and orthopedic management in a patiente pediatric
Liliana Mejia de Beldjenna (Cali, Colombia)
P171
Vitamin D levels and signs of metabolic bone disease in Adolescents with Idiopathic Scoliosis
Andreas Kouklinos (London, UK)
P172
Longitudinal assessment of spinal bone mineral density (BMD) in children with neurofibromatosis type 1 (NF1) using Dual Energy Absorptiometry (DXA) and Quantitative computed tomography (QCT)
M Zulf Mughal (Manchester, UK)
P173
Vitamin D Prescription: A review of British National Formulary for Children recommendations, and a proposal
Andreas Kouklinos (London, UK)
P174
Elite child athlete is our future: bone lumbar spine adaptation in egyptian children monofin athletes
Magdy Abouzeid (Alexandria, Egypt)
P175
Correlation analysis of bone vibration frequency and its mass-volume ratio
Hajar Razaghi (Sheffield, UK)
P176
One case of pseudohypoparathyroidism, clinical caracterisation, follow up and treatment
Juan Javier Lamoglia (Cali, Colombia)
P177
The bone mineral density of children with CF
Marie Roddy (Dublin, Ireland)
P178
Hypomagnesaemia with hypercalciuria secondary to mutations in the Claudin gene: a single centre experience
Shaila Sukthankar (Manchester, UK)
P179
The impact of selective serotonin reuptake inhibitors on bone mineral density in the pediatric and young adult population
Maria Vogiatzi (New York, USA)
P180
Beyond brittle bones: a preliminary report from the Osteogenesis Imperfecta Adult Natural History Initiative
Laura Tosi (Washington DC, USA)
P181
Long-term imiglucerase/alglucerase treatment in Latin American children with type 1 Gaucher disease: Lessons from the International Collaborative Gaucher Group (ICGG) Gaucher Registry
Jose Camelo (Arlington, USA)
P182
Reference curves for Bone Health Index for Han children from five large cities in China, and a comparison to Asian-American children
Hans Henrik Thodberg (Holte, Denmark)
P183
Juvenile Idiopathic Osteoporosis - a case study
Ciara McDonnell (Dublin, Ireland)
P184
High FGF23 measurements in a child with Vitamin D dependent rickets type I: cause or consequence?
Ciara McDonnell (Dublin, Ireland)
P185
An unusual presentation of progressive osseous heteroplasia in a 7-year-old female child
Dirk Schrander (Maastricht, Netherlands)
P186
Bone mass, bone microarchitecture (TBS) and anthropometric measurements during childhood growth in Spanish girls
Renaud Winzenrieth (Pessac, France)
P187
Juvenile Idiopathic Osteoporosis responsive to intravenous Alendronate
Miguel Angel Guagnelli (Barcelona, Spain)
P188
Abstract withdrawn
P189
Clinical features of temporary brittle bone disease
Colin Paterson (Dundee, UK)
P190
Vitamin D deficiency rickets in neonates
Colin Paterson (Dundee, UK)
P191
Long-term follow-up in Stuve–Wiedemann Syndrome: A case report
Paola Sabrina Buonuomo (Rome, Italy)
P192
The assessement of the vitamin D supply in the population of Polish children at the age of 9-12 years – multicentre research- preliminary report
Joanna Golec (Lodz, Poland)
P193
The effect of levothyroxine therapy on vitamin D and bone mineral density
Behzat Ozkan (Izmir, Turkey)
P194
Celiac disease underlying rickets in an adolescent
Behzat Ozkan (Izmir, Turkey)
P195
A case of progressive generalised osteolysis – a fibrous dysplasia or something else?
Veselin Boyadzhiev (Varna, Bulgaria)
P196
Bigger but not stronger? Growth hormone treatment in Turner Syndrome may confer no benefit to HR-pQCT determined bone micro-architecture
Munier Nour (Calgary, Canada)
P197
Parathyroid hormone administered by continuous subcutaneous infusion is more effective than when given by intermittent injection
Jeremy Allgrove (London, UK)
P198
Severe hypercalcemia in an infant with idiopathic infantile hypercalcemia caused by mutation in CYP24A1 gene
Grazia Morandi (Verona, Italy)
P199
Levels of 25(OH)vitamin D in children and adolescents with Type 1 Diabetes Mellitus and in healthy controls in Bulgarian population
Olga Slavcheva (Sofia, Bulgaria)
P200
Low 25-hydroxyvitamin D levels in Scheuermann's disease: a preliminary study of nineteen patients
Edward Southern (Slidell, USA)
P201
Guided growth with hinge plates for lack of extension and fixed flexion of the knee
Miguel Galban (Caracas, Venezuela)